A single-cell mass cytometry platform to map the effects of preclinical drugs on cartilage homeostasis

No disease-modifying drug exists for osteoarthritis (OA). Despite success in animal models, candidate drugs continue to fail in clinical trials owing to the unmapped interpatient heterogeneity and disease complexity. We used a single-cell platform based on cytometry by time-of-flight (cyTOF) to prec...

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Detalles Bibliográficos
Autores principales: Sahu, Neety, Grandi, Fiorella Carla, Bhutani, Nidhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744259/
https://www.ncbi.nlm.nih.gov/pubmed/36194485
http://dx.doi.org/10.1172/jci.insight.160702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744259/
https://www.ncbi.nlm.nih.gov/pubmed/36194485
http://dx.doi.org/10.1172/jci.insight.160702

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