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Genetic duplication of tissue factor reveals subfunctionalization in venous and arterial hemostasis

Tissue factor (TF) is an evolutionarily conserved protein necessary for initiation of hemostasis. Zebrafish have two copies of the tissue factor gene (f3a and f3b) as the result of an ancestral teleost fish duplication event (so called ohnologs). In vivo physiologic studies of TF function have been...

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Detalles Bibliográficos
Autores principales:	Grzegorski, Steven J., Zhao, Yakun, Richter, Catherine E., Ku, Chia-Jui, Lavik, Kari I., Paul, Divyani, Morrissey, James H., Shavit, Jordan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744294/ https://www.ncbi.nlm.nih.gov/pubmed/36449521 http://dx.doi.org/10.1371/journal.pgen.1010534

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