Co-depletion of NIPBL and WAPL balance cohesin activity to correct gene misexpression

The relationship between cohesin-mediated chromatin looping and gene expression remains unclear. NIPBL and WAPL are two opposing regulators of cohesin activity; depletion of either is associated with changes in both chromatin folding and transcription across a wide range of cell types. However, a di...

Descripción completa

Detalles Bibliográficos
Autores principales: Luppino, Jennifer M., Field, Andrew, Nguyen, Son C., Park, Daniel S., Shah, Parisha P., Abdill, Richard J., Lan, Yemin, Yunker, Rebecca, Jain, Rajan, Adelman, Karen, Joyce, Eric F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744307/
https://www.ncbi.nlm.nih.gov/pubmed/36449519
http://dx.doi.org/10.1371/journal.pgen.1010528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744307/
https://www.ncbi.nlm.nih.gov/pubmed/36449519
http://dx.doi.org/10.1371/journal.pgen.1010528

Ejemplares similares