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Co-depletion of NIPBL and WAPL balance cohesin activity to correct gene misexpression

The relationship between cohesin-mediated chromatin looping and gene expression remains unclear. NIPBL and WAPL are two opposing regulators of cohesin activity; depletion of either is associated with changes in both chromatin folding and transcription across a wide range of cell types. However, a di...

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Detalles Bibliográficos
Autores principales:	Luppino, Jennifer M., Field, Andrew, Nguyen, Son C., Park, Daniel S., Shah, Parisha P., Abdill, Richard J., Lan, Yemin, Yunker, Rebecca, Jain, Rajan, Adelman, Karen, Joyce, Eric F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744307/ https://www.ncbi.nlm.nih.gov/pubmed/36449519 http://dx.doi.org/10.1371/journal.pgen.1010528

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