Incidental Appendiceal Basidiobolomycosis in a Clinical Setting of Intestinal Intussusception in a Five-Year-Old Patient: A Case Report

Gastrointestinal basidiobolomycosis (GIB) is a rare, critical fungal infection caused by Basidiobolus ranarum, an environmental saprophyte with a wide geographical distribution. It usually affects the immunocompetent host and presents with nonspecific clinical signs and symptoms, posing a diagnostic and therapeutic challenge. The coexistence of GIB and intussusception is rare, and it is far more unusual for appendiceal basidiobolomycosis and intussusception to coexist. Herein, we report a case of a five-year-old male who presented to the emergency department with a clinical and radiological picture of intestinal intussusception, for which he underwent laparoscopic exploration and reduction. The appendix was observed to be partially invaginated through the cecum and was difficult to be reduced. Subsequent histopathological examination of the laparoscopically resected appendix demonstrated fungal organisms morphologically consistent with basidiobolomycosis. The patient achieved full recovery with a combination of surgery and prolonged antifungal therapy.