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VPS9D1-AS1 overexpression amplifies intratumoral TGF-β signaling and promotes tumor cell escape from CD8(+) T cell killing in colorectal cancer

Efficacy of immunotherapy is limited in patients with colorectal cancer (CRC) because high expression of tumor-derived transforming growth factor (TGF)-β pathway molecules and interferon (IFN)-stimulated genes (ISGs) promotes tumor immune evasion. Here, we identified a long noncoding RNA (lncRNA), V...

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Detalles Bibliográficos
Autores principales:	Yang, Lei, Dong, Xichen, Liu, Zheng, Tan, Jinjing, Huang, Xiaoxi, Wen, Tao, Qu, Hao, Wang, Zhenjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744440/ https://www.ncbi.nlm.nih.gov/pubmed/36458816 http://dx.doi.org/10.7554/eLife.79811

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