Cargando…

Immunogenicity and efficacy of recombinant subunit SARS-CoV-2 vaccine candidate in the Syrian hamster model

SARS-CoV-2 causes devastating impact on the human population and has become a major public health concern. The frequent emergence of SARS-CoV-2 variants of concern urges the development of safe and efficacious vaccine against SARS-CoV-2 variants. We developed a candidate vaccine Baiya SARS-CoV-2 Vax...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shanmugaraj, Balamurugan, Khorattanakulchai, Narach, Paungpin, Weena, Akkhawattanangkul, Yada, Manopwisedjaroen, Suwimon, Thitithanyanont, Arunee, Phoolcharoen, Waranyoo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744481/ https://www.ncbi.nlm.nih.gov/pubmed/36533163 http://dx.doi.org/10.1016/j.btre.2022.e00779

Ejemplares similares

A recombinant subunit vaccine candidate produced in plants elicits neutralizing antibodies against SARS-CoV-2 variants in macaques
por: Khorattanakulchai, Narach, et al.
Publicado: (2022)

Monoclonal Antibodies B38 and H4 Produced in Nicotiana benthamiana Neutralize SARS-CoV-2 in vitro
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2020)

Immunogenicity Studies of Plant-Produced SARS-CoV-2 Receptor Binding Domain-Based Subunit Vaccine Candidate with Different Adjuvant Formulations
por: Siriwattananon, Konlavat, et al.
Publicado: (2021)

Rapid production of SARS-CoV-2 receptor binding domain (RBD) and spike specific monoclonal antibody CR3022 in Nicotiana benthamiana
por: Rattanapisit, Kaewta, et al.
Publicado: (2020)

Preclinical evaluation of immunogenicity, efficacy and safety of a recombinant plant-based SARS-CoV-2 RBD vaccine formulated with 3M-052-Alum adjuvant
por: Phoolcharoen, Waranyoo, et al.
Publicado: (2023)

Preclinical evaluation of a plant-derived SARS-CoV-2 subunit vaccine: Protective efficacy, immunogenicity, safety, and toxicity
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2022)

SARS‐CoV‐2 omicron variant: Could it be another threat?
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2022)

Plant-Produced S1 Subunit Protein of SARS-CoV-2 Elicits Immunogenic Responses in Mice
por: Panapitakkul, Chalisa, et al.
Publicado: (2022)

Development of Plant-Produced Recombinant ACE2-Fc Fusion Protein as a Potential Therapeutic Agent Against SARS-CoV-2
por: Siriwattananon, Konlavat, et al.
Publicado: (2021)

Plant-produced SARS-CoV-2 receptor binding domain (RBD) variants showed differential binding efficiency with anti-spike specific monoclonal antibodies
por: Rattanapisit, Kaewta, et al.
Publicado: (2021)

Potential for Developing Plant-Derived Candidate Vaccines and Biologics against Emerging Coronavirus Infections
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2021)

Recombinant human dentin matrix protein 1 (DMP1) induces the osteogenic differentiation of human periodontal ligament cells
por: Ahmad, Aktsar Roskiana, et al.
Publicado: (2019)

Recombinant Human Dentin Matrix Protein 1 (hDMP1) Expressed in Nicotiana benthamiana Potentially Induces Osteogenic Differentiation
por: Ahmad, Aktsar Roskiana, et al.
Publicado: (2019)

Plant Molecular Farming: A Viable Platform for Recombinant Biopharmaceutical Production
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2020)

Functional Characterization of Pembrolizumab Produced in Nicotiana benthamiana Using a Rapid Transient Expression System
por: Phakham, Tanapati, et al.
Publicado: (2021)

Development of SARS-CoV-2 neutralizing antibody detection assay by using recombinant plant-produced proteins
por: Jirarojwattana, Perawat, et al.
Publicado: (2023)

Emergence of Novel Coronavirus 2019-nCoV: Need for Rapid Vaccine and Biologics Development
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2020)

Pharmacological Activities of Fingerroot Extract and Its Phytoconstituents Against SARS-CoV-2 Infection in Golden Syrian Hamsters
por: Kongratanapasert, Teetat, et al.
Publicado: (2023)

Plant-Produced Receptor-Binding Domain of SARS-CoV-2 Elicits Potent Neutralizing Responses in Mice and Non-human Primates
por: Siriwattananon, Konlavat, et al.
Publicado: (2021)

Harnessing the Potential of Plant Expression System towards the Production of Vaccines for the Prevention of Human Papillomavirus and Cervical Cancer
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2022)

Virus MIP-composites for SARS-CoV-2 detection in the aquatic environment
por: Sukjee, Wannisa, et al.
Publicado: (2022)

Biotechnological Insights on the Expression and Production of Antimicrobial Peptides in Plants
por: Shanmugaraj, Balamurugan, et al.
Publicado: (2021)

Rapid and Efficient Cell-to-Cell Transmission of Avian Influenza H5N1 Virus in MDCK Cells Is Achieved by Trogocytosis
por: Kongsomros, Supasek, et al.
Publicado: (2021)

Expression and Functional Evaluation of Recombinant Anti-receptor Activator of Nuclear Factor Kappa-B Ligand Monoclonal Antibody Produced in Nicotiana benthamiana
por: Boonyayothin, Wanuttha, et al.
Publicado: (2021)

Expression optimization, purification and in vitro characterization of human epidermal growth factor produced in Nicotiana benthamiana
por: Hanittinan, Oranicha, et al.
Publicado: (2020)

Antitumor effect of plant-produced anti-CTLA-4 monoclonal antibody in a murine model of colon cancer
por: Bulaon, Christine Joy I., et al.
Publicado: (2023)

Plant-produced recombinant SARS-CoV-2 receptor-binding domain; an economical, scalable biomaterial source for COVID-19 diagnosis
por: Rattanapisit, Kaewta, et al.
Publicado: (2021)

Trogocytosis with monocytes associated with increased α2,3 sialic acid expression on B cells during H5N1 influenza virus infection
por: Kongsomros, Supasek, et al.
Publicado: (2020)

Synergistic anti-SARS-CoV-2 activity of repurposed anti-parasitic drug combinations
por: Jitobaom, Kunlakanya, et al.
Publicado: (2022)

Rapid transient expression of functional human vascular endothelial growth factor in Nicotiana benthamiana and characterization of its biological activity
por: Bulaon, Christine Joy I., et al.
Publicado: (2020)

Anti-SARS-CoV-2 Activity of Extracellular Vesicle Inhibitors: Screening, Validation, and Combination with Remdesivir
por: Kongsomros, Supasek, et al.
Publicado: (2021)

Systematic Exploration of SARS-CoV-2 Adaptation to Vero E6, Vero E6/TMPRSS2, and Calu-3 Cells
por: Aiewsakun, Pakorn, et al.
Publicado: (2023)

Immunodominant linear B cell epitopes in the spike and membrane proteins of SARS-CoV-2 identified by immunoinformatics prediction and immunoassay
por: Polyiam, Kanokporn, et al.
Publicado: (2021)

Mice Immunized with the Vaccine Candidate HexaPro Spike Produce Neutralizing Antibodies against SARS-CoV-2
por: Seephetdee, Chotiwat, et al.
Publicado: (2021)

Target Enrichment Metagenomics Reveals Human Pegivirus-1 in Pediatric Hematopoietic Stem Cell Transplantation Recipients
por: Ludowyke, Natali, et al.
Publicado: (2022)

Immunogenicity and protective efficacy of BBV152, whole virion inactivated SARS- CoV-2 vaccine candidates in the Syrian hamster model
por: Mohandas, Sreelekshmy, et al.
Publicado: (2021)

LYMPHOCYTIC CHORIOMENINGITIS IN THE SYRIAN HAMSTER
por: Smadel, J. E., et al.
Publicado: (1942)

The Experimental Use of Syrian Hamsters
por: Valentine, Helen, et al.
Publicado: (2012)

Immunogenicity and Tolerability of a SARS-CoV-2 TNX-1800, a Live Recombinant Poxvirus Vaccine Candidate, in Syrian Hamsters and New Zealand White Rabbits
por: Awasthi, Mayanka, et al.
Publicado: (2023)

SARS‐CoV‐2 neutralizing antibodies decline over one year and patients with severe COVID‐19 pneumonia display a unique cytokine profile
por: Vacharathit, Vimvara, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0hmsjdiv97qgateui0s1im3fek