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Latrophilin‐3 heterozygous versus homozygous mutations in Sprague Dawley rats: Effects on egocentric and allocentric memory and locomotor activity

Latrophilin‐3 (LPHN3) is a brain specific G‐protein coupled receptor associated with increased risk of attention deficit hyperactivity disorder (ADHD) and cognitive deficits. CRISPR/Cas9 was used to generate a constitutive knockout (KO) rat of Lphn3 by deleting exon 3, based on human data that LPHN3...

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Detalles Bibliográficos
Autores principales:	Regan, Samantha L., Sugimoto, Chiho, Dawson, Hannah E., Williams, Michael T., Vorhees, Charles V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744505/ https://www.ncbi.nlm.nih.gov/pubmed/35985692 http://dx.doi.org/10.1111/gbb.12817

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