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In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein (Advanced Genetics 1/03)

Extracellular Vesicle Imaging Cancer cell‐derived extracellular vesicles (EVs) promote tumor growth and spread. Studying the distribution of EVs in the body is key to understanding cancer progression and developing therapies. In article number 2100055, Masamitsu Kanada and co‐workers develop a highl...

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Detalles Bibliográficos
Autores principales: Perez, Gloria I., Broadbent, David, Zarea, Ahmed A., Dolgikh, Benedikt, Bernard, Matthew P., Withrow, Alicia, McGill, Amelia, Toomajian, Victoria, Thampy, Lukose K., Harkema, Jack, Walker, Joel R., Kirkland, Thomas A., Bachmann, Michael H., Schmidt, Jens, Kanada, Masamitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744535/
http://dx.doi.org/10.1002/ggn2.202270011
Descripción
Sumario:Extracellular Vesicle Imaging Cancer cell‐derived extracellular vesicles (EVs) promote tumor growth and spread. Studying the distribution of EVs in the body is key to understanding cancer progression and developing therapies. In article number 2100055, Masamitsu Kanada and co‐workers develop a highly sensitive EV reporter for tracking heterogeneous EV populations released from cancer cells in live mice. [Image: see text]