Sex‐specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal and analgesia

Opioids like fentanyl remain the mainstay treatment for chronic pain. Unfortunately, opioid's high dependence liability has led to the current opioid crisis, in part, because of side‐effects that develop during long‐term use, including analgesic tolerance and physical dependence. Both tolerance...

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Detalles Bibliográficos
Autores principales: Puig, Stephanie, Shelton, Micah A., Barko, Kelly, Seney, Marianne L., Logan, Ryan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744556/
https://www.ncbi.nlm.nih.gov/pubmed/36053258
http://dx.doi.org/10.1111/gbb.12829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744556/
https://www.ncbi.nlm.nih.gov/pubmed/36053258
http://dx.doi.org/10.1111/gbb.12829

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