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Sex‐specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal and analgesia
Opioids like fentanyl remain the mainstay treatment for chronic pain. Unfortunately, opioid's high dependence liability has led to the current opioid crisis, in part, because of side‐effects that develop during long‐term use, including analgesic tolerance and physical dependence. Both tolerance...
Autores principales: | Puig, Stephanie, Shelton, Micah A., Barko, Kelly, Seney, Marianne L., Logan, Ryan W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744556/ https://www.ncbi.nlm.nih.gov/pubmed/36053258 http://dx.doi.org/10.1111/gbb.12829 |
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