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The complexity of ventral CA1 and its multiple functionalities

The hippocampus is one of the most widely investigated brain regions with its massive contributions to multiple behaviours. Especially, the hippocampus is subdivided into the dorsal and ventral parts playing distinct roles. In this review, we will focus on the ventral hippocampus, especially the ven...

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Detalles Bibliográficos
Autores principales: Hong, Ilgang, Kaang, Bong‐Kiun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744572/
https://www.ncbi.nlm.nih.gov/pubmed/35815710
http://dx.doi.org/10.1111/gbb.12826
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author Hong, Ilgang
Kaang, Bong‐Kiun
author_facet Hong, Ilgang
Kaang, Bong‐Kiun
author_sort Hong, Ilgang
collection PubMed
description The hippocampus is one of the most widely investigated brain regions with its massive contributions to multiple behaviours. Especially, the hippocampus is subdivided into the dorsal and ventral parts playing distinct roles. In this review, we will focus on the ventral hippocampus, especially the ventral CA1 (vCA1), whose role is being actively discovered. vCA1 is well known to be associated with emotion‐like behaviour, in both positive (reward) and negative (aversive) stimuli. How can this small region in volume mediate such variety of responses? This question will be answered with technologies up to date that have allowed us to study in‐depth the specific neural circuit and to map the complex connectivity.
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spelling pubmed-97445722023-02-08 The complexity of ventral CA1 and its multiple functionalities Hong, Ilgang Kaang, Bong‐Kiun Genes Brain Behav Review Article The hippocampus is one of the most widely investigated brain regions with its massive contributions to multiple behaviours. Especially, the hippocampus is subdivided into the dorsal and ventral parts playing distinct roles. In this review, we will focus on the ventral hippocampus, especially the ventral CA1 (vCA1), whose role is being actively discovered. vCA1 is well known to be associated with emotion‐like behaviour, in both positive (reward) and negative (aversive) stimuli. How can this small region in volume mediate such variety of responses? This question will be answered with technologies up to date that have allowed us to study in‐depth the specific neural circuit and to map the complex connectivity. Blackwell Publishing Ltd 2022-07-11 /pmc/articles/PMC9744572/ /pubmed/35815710 http://dx.doi.org/10.1111/gbb.12826 Text en © 2022 The Authors. Genes, Brain and Behavior published by International Behavioural and Neural Genetics Society and John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review Article
Hong, Ilgang
Kaang, Bong‐Kiun
The complexity of ventral CA1 and its multiple functionalities
title The complexity of ventral CA1 and its multiple functionalities
title_full The complexity of ventral CA1 and its multiple functionalities
title_fullStr The complexity of ventral CA1 and its multiple functionalities
title_full_unstemmed The complexity of ventral CA1 and its multiple functionalities
title_short The complexity of ventral CA1 and its multiple functionalities
title_sort complexity of ventral ca1 and its multiple functionalities
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744572/
https://www.ncbi.nlm.nih.gov/pubmed/35815710
http://dx.doi.org/10.1111/gbb.12826
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