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MicroRNA-101-3p Suppresses mTOR and Causes Mitochondrial Fragmentation and Cell Degeneration in COPD

BACKGROUND: Cigarette smoke is assumed to cause the loss of airway wall structure in chronic obstructive pulmonary disease (COPD) by reducing airway smooth muscle cell (ASMC) function. It also modifies mTOR activity, microRNA (miR)-101-3p expression, and mitochondria function. Here, the link between...

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Detalles Bibliográficos
Autores principales: Fang, Lei, Wang, Xinggang, Zhang, Ming, Khan, Petra, Tamm, Michael, Roth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744603/
https://www.ncbi.nlm.nih.gov/pubmed/36518817
http://dx.doi.org/10.1155/2022/5933324