Cold-adapted SARS-CoV-2 variants with different temperature sensitivity exhibit an attenuated phenotype and confer protective immunity

As novel SARS-CoV-2 Variants of Concern emerge, the efficacy of existing vaccines against COVID-19 is declining. A possible solution to this problem lies in the development of a live attenuated vaccine potentially able of providing cross-protective activity against a wide range of SARS-CoV-2 antigen...

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Detalles Bibliográficos
Autores principales: Faizuloev, Evgeny, Gracheva, Anastasiia, Korchevaya, Ekaterina, Smirnova, Daria, Samoilikov, Roman, Pankratov, Andrey, Trunova, Galina, Khokhlova, Varvara, Ammour, Yulia, Petrusha, Olga, Poromov, Artem, Leneva, Irina, Svitich, Oxana, Zverev, Vitaly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744683/
https://www.ncbi.nlm.nih.gov/pubmed/36528447
http://dx.doi.org/10.1016/j.vaccine.2022.12.019

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