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Evaluating Islatravir Administered Via Microneedle Array Patch for Long-Acting HIV Pre-exposure Prophylaxis Using Physiologically Based Pharmacokinetic Modelling
BACKGROUND AND OBJECTIVES: Technologies for long-acting administration of antiretrovirals (ARVs) for the prevention and treatment of HIV are at the forefront of research initiatives aiming to tackle issues surrounding drug adherence with the current standard of once-daily oral administration. Islatr...
Autores principales: | Kinvig, Hannah, Cottura, Nicolas, Lloyd, Andrew, Frivold, Collrane, Mistilis, Jessica, Jarrahian, Courtney, Siccardi, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744694/ https://www.ncbi.nlm.nih.gov/pubmed/36178586 http://dx.doi.org/10.1007/s13318-022-00793-6 |
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