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Spesolimab: First Approval
Spesolimab (spesolimab-sbzo; SPEVIGO(®)) is an interleukin (IL)-36 receptor antagonist being developed by Boehringer Ingelheim for the treatment of various immune-mediated disorders. In September 2022, spesolimab was approved in the USA for the treatment of generalized pustular psoriasis (GPP) flare...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer International Publishing
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744699/ https://www.ncbi.nlm.nih.gov/pubmed/36418672 http://dx.doi.org/10.1007/s40265-022-01801-4 |
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author | Blair, Hannah A. |
author_facet | Blair, Hannah A. |
author_sort | Blair, Hannah A. |
collection | PubMed |
description | Spesolimab (spesolimab-sbzo; SPEVIGO(®)) is an interleukin (IL)-36 receptor antagonist being developed by Boehringer Ingelheim for the treatment of various immune-mediated disorders. In September 2022, spesolimab was approved in the USA for the treatment of generalized pustular psoriasis (GPP) flares in adults. This article summarizes the milestones in the development of spesolimab leading to this first approval for GPP flares. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40265-022-01801-4. |
format | Online Article Text |
id | pubmed-9744699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-97446992022-12-14 Spesolimab: First Approval Blair, Hannah A. Drugs AdisInsight Report Spesolimab (spesolimab-sbzo; SPEVIGO(®)) is an interleukin (IL)-36 receptor antagonist being developed by Boehringer Ingelheim for the treatment of various immune-mediated disorders. In September 2022, spesolimab was approved in the USA for the treatment of generalized pustular psoriasis (GPP) flares in adults. This article summarizes the milestones in the development of spesolimab leading to this first approval for GPP flares. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40265-022-01801-4. Springer International Publishing 2022-11-23 2022 /pmc/articles/PMC9744699/ /pubmed/36418672 http://dx.doi.org/10.1007/s40265-022-01801-4 Text en © Springer Nature 2022, corrected publication 2022 https://creativecommons.org/licenses/by-nc/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | AdisInsight Report Blair, Hannah A. Spesolimab: First Approval |
title | Spesolimab: First Approval |
title_full | Spesolimab: First Approval |
title_fullStr | Spesolimab: First Approval |
title_full_unstemmed | Spesolimab: First Approval |
title_short | Spesolimab: First Approval |
title_sort | spesolimab: first approval |
topic | AdisInsight Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744699/ https://www.ncbi.nlm.nih.gov/pubmed/36418672 http://dx.doi.org/10.1007/s40265-022-01801-4 |
work_keys_str_mv | AT blairhannaha spesolimabfirstapproval |