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SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice

Brown adipose tissue plays a central role in the regulation of the energy balance by expending energy to produce heat. NAD(+)-dependent deacylase sirtuins have widely been recognized as positive regulators of brown adipose tissue thermogenesis. However, here we reveal that SIRT7, one of seven mammal...

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Detalles Bibliográficos
Autores principales: Yoshizawa, Tatsuya, Sato, Yoshifumi, Sobuz, Shihab U., Mizumoto, Tomoya, Tsuyama, Tomonori, Karim, Md. Fazlul, Miyata, Keishi, Tasaki, Masayoshi, Yamazaki, Masaya, Kariba, Yuichi, Araki, Norie, Araki, Eiichi, Kajimura, Shingo, Oike, Yuichi, Braun, Thomas, Bober, Eva, Auwerx, Johan, Yamagata, Kazuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744749/
https://www.ncbi.nlm.nih.gov/pubmed/36509749
http://dx.doi.org/10.1038/s41467-022-35219-z