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SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice
Brown adipose tissue plays a central role in the regulation of the energy balance by expending energy to produce heat. NAD(+)-dependent deacylase sirtuins have widely been recognized as positive regulators of brown adipose tissue thermogenesis. However, here we reveal that SIRT7, one of seven mammal...
Autores principales: | Yoshizawa, Tatsuya, Sato, Yoshifumi, Sobuz, Shihab U., Mizumoto, Tomoya, Tsuyama, Tomonori, Karim, Md. Fazlul, Miyata, Keishi, Tasaki, Masayoshi, Yamazaki, Masaya, Kariba, Yuichi, Araki, Norie, Araki, Eiichi, Kajimura, Shingo, Oike, Yuichi, Braun, Thomas, Bober, Eva, Auwerx, Johan, Yamagata, Kazuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744749/ https://www.ncbi.nlm.nih.gov/pubmed/36509749 http://dx.doi.org/10.1038/s41467-022-35219-z |
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