Low-dose IL-2 improved clinical symptoms by restoring reduced regulatory T cells in patients with refractory rheumatoid arthritis: A randomized controlled trial

BACKGROUND: Regulatory T cells (Tregs) have been found to play crucial roles in immune tolerance. However, the status of Tregs in refractory rheumatoid arthritis (RA) is still unclear. Moreover, low-dose interleukin-2 (IL-2) has been reported to selectively promote the expansion of Tregs. This study...

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Detalles Bibliográficos
Autores principales: Wang, Jia, Zhang, Sheng-Xiao, Chang, Jia-Song, Cheng, Ting, Jiang, Xiao-Jing, Su, Qin-Yi, Zhang, Jia-Qi, Luo, Jing, Li, Xiao-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744779/
https://www.ncbi.nlm.nih.gov/pubmed/36524114
http://dx.doi.org/10.3389/fimmu.2022.947341

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