Tumor fractions deciphered from circulating cell-free DNA methylation for cancer early diagnosis

Tumor-derived circulating cell-free DNA (cfDNA) provides critical clues for cancer early diagnosis, yet it often suffers from low sensitivity. Here, we present a cancer early diagnosis approach using tumor fractions deciphered from circulating cfDNA methylation signatures. We show that the estimated...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao, Cheng, Zhen, Dong, Mingyu, Liu, Qi, Yang, Weiyang, Liu, Min, Tian, Junzhang, Cheng, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744803/
https://www.ncbi.nlm.nih.gov/pubmed/36509772
http://dx.doi.org/10.1038/s41467-022-35320-3

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