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scATAC-Seq reveals heterogeneity associated with spermatogonial differentiation in cultured male germline stem cells
Spermatogonial stem cells are the most primitive spermatogonia in testis, which can self-renew to maintain the stem cell pool or differentiate to give rise to germ cells including haploid spermatids. All-trans-retinoic acid (RA), a bioactive metabolite of vitamin A, plays a fundamental role in initi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744833/ https://www.ncbi.nlm.nih.gov/pubmed/36509798 http://dx.doi.org/10.1038/s41598-022-25729-7 |