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scATAC-Seq reveals heterogeneity associated with spermatogonial differentiation in cultured male germline stem cells

Spermatogonial stem cells are the most primitive spermatogonia in testis, which can self-renew to maintain the stem cell pool or differentiate to give rise to germ cells including haploid spermatids. All-trans-retinoic acid (RA), a bioactive metabolite of vitamin A, plays a fundamental role in initi...

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Detalles Bibliográficos
Autores principales: Suen, Hoi Ching, Luk, Alfred Chun Shui, Liao, Jinyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744833/
https://www.ncbi.nlm.nih.gov/pubmed/36509798
http://dx.doi.org/10.1038/s41598-022-25729-7

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