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L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary

Most ovarian high-grade serous carcinomas (HGSC) arise from Serous Tubal Intraepithelial Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC lesions from FT secretory cells leads to seeding of the ovarian surface, with rapid tumor dissemination to other abdominal...

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Detalles Bibliográficos
Autores principales: Doberstein, Kai, Spivak, Rebecca, Reavis, Hunter D., Hooda, Jagmohan, Feng, Yi, Kroeger, Paul T., Stuckelberger, Sarah, Mills, Gordon B., Devins, Kyle M., Schwartz, Lauren E., Iwanicki, Marcin P., Fogel, Mina, Altevogt, Peter, Drapkin, Ronny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744873/
https://www.ncbi.nlm.nih.gov/pubmed/36509990
http://dx.doi.org/10.1038/s42003-022-04314-8