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L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Most ovarian high-grade serous carcinomas (HGSC) arise from Serous Tubal Intraepithelial Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC lesions from FT secretory cells leads to seeding of the ovarian surface, with rapid tumor dissemination to other abdominal...
Autores principales: | Doberstein, Kai, Spivak, Rebecca, Reavis, Hunter D., Hooda, Jagmohan, Feng, Yi, Kroeger, Paul T., Stuckelberger, Sarah, Mills, Gordon B., Devins, Kyle M., Schwartz, Lauren E., Iwanicki, Marcin P., Fogel, Mina, Altevogt, Peter, Drapkin, Ronny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744873/ https://www.ncbi.nlm.nih.gov/pubmed/36509990 http://dx.doi.org/10.1038/s42003-022-04314-8 |
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