Regulation of bone homeostasis by MERTK and TYRO3

The fine equilibrium of bone homeostasis is maintained by bone-forming osteoblasts and bone-resorbing osteoclasts. Here, we show that TAM receptors MERTK and TYRO3 exert reciprocal effects in osteoblast biology: Osteoblast-targeted deletion of MERTK promotes increased bone mass in healthy mice and m...

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Detalles Bibliográficos
Autores principales: Engelmann, Janik, Zarrer, Jennifer, Gensch, Victoria, Riecken, Kristoffer, Berenbrok, Nikolaus, Luu, The Vinh, Beitzen-Heineke, Antonia, Vargas-Delgado, Maria Elena, Pantel, Klaus, Bokemeyer, Carsten, Bhamidipati, Somasekhar, Darwish, Ihab S., Masuda, Esteban, Burstyn-Cohen, Tal, Alberto, Emily J., Ghosh, Sourav, Rothlin, Carla, Hesse, Eric, Taipaleenmäki, Hanna, Ben-Batalla, Isabel, Loges, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744875/
https://www.ncbi.nlm.nih.gov/pubmed/36509738
http://dx.doi.org/10.1038/s41467-022-33938-x

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