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Idarubicin combats abiraterone and enzalutamide resistance in prostate cells via targeting XPA protein
Although second-generation therapies like abiraterone (ABI) and enzalutamide (ENZ) benefit patients with castration-resistant prostate cancer (CRPC), drug resistance frequently occurs, eventually resulting in therapy failure. In this study, we used two libraries, FDA-approved drug library and CRISP/...
Autores principales: | Zhang, Ying, Wei, Wei, Li, Changying, Yan, Siyuan, Wang, Shanshan, Xiao, Shudong, He, Chenchen, Li, Jing, Qi, Zhi, Li, Benyi, Yang, Kuo, Li, Changlin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744908/ https://www.ncbi.nlm.nih.gov/pubmed/36509750 http://dx.doi.org/10.1038/s41419-022-05490-5 |
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