Lymphopenia during (177)Lu-DOTATATE therapy leading to recurrence of tuberculosis: a case report

We report the case of a 72-year-old woman who presented with tuberculous arthritis during the setting of (177)Lu-DOTATATE therapy for a grade-2 neuro-endocrine pancreatic tumor with liver metastases. We hypothesized that this recurrence might have been related to the occurrence of lymphopenia, which...

Descripción completa

Detalles Bibliográficos
Autores principales: Boughdad, Sarah, Da Mota, Michael, Mendes De Carvalho, Mélanie, Firsova, Maria, Prior, John O., Schaefer, Niklaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9744994/
https://www.ncbi.nlm.nih.gov/pubmed/36510100
http://dx.doi.org/10.1186/s41824-022-00157-y
Descripción
Sumario:We report the case of a 72-year-old woman who presented with tuberculous arthritis during the setting of (177)Lu-DOTATATE therapy for a grade-2 neuro-endocrine pancreatic tumor with liver metastases. We hypothesized that this recurrence might have been related to the occurrence of lymphopenia, which is common during PRRT. Indeed, though lymphopenia is frequently dismissed, it could lead to the development of opportunistic diseases and its severity should be examined, especially in case of abnormal clinical symptoms. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s41824-022-00157-y.

Ejemplares similares