Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice

Dopamine (DA) neurons are primarily concentrated in substantia nigra (SN) and ventral tegmental area (VTA). A subset of these neurons expresses the neurotensin receptor NTSR1 and its putative ligand neurotensin (Nts). NTSR1, a G protein-coupled receptor (GPCR), which classically activates Gαq/calciu...

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Detalles Bibliográficos
Autores principales: Ehrlich, Aliza T., Couvineau, Pierre, Schamiloglu, Selin, Wojcik, Stefan, Da Fonte, Dillon, Mezni, Amina, von Zastrow, Mark, Bender, Kevin J., Bouvier, Michel, Kieffer, Brigitte L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745132/
https://www.ncbi.nlm.nih.gov/pubmed/36523815
http://dx.doi.org/10.3389/fncel.2022.1076599

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