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Inhibiting 5‐lipoxygenase prevents skeletal muscle atrophy by targeting organogenesis signalling and insulin‐like growth factor‐1

BACKGROUND: Skeletal muscle atrophy can occur in response to numerous factors, such as ageing and certain medications, and produces a major socio‐economic burden. At present, there are no approved drugs for treating skeletal muscle atrophy. Arachidonate 5‐lipoxygenase (Alox5) is a drug target for a...

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Detalles Bibliográficos
Autores principales:	Kim, Hyun‐Jun, Kim, Seon‐Wook, Lee, Sang‐Hoon, Jung, Da‐Woon, Williams, Darren R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745465/ https://www.ncbi.nlm.nih.gov/pubmed/36221153 http://dx.doi.org/10.1002/jcsm.13092

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