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Pyruvate dehydrogenase kinase 4 promotes ubiquitin–proteasome system‐dependent muscle atrophy

BACKGROUND: Muscle atrophy, leading to muscular dysfunction and weakness, is an adverse outcome of sustained period of glucocorticoids usage. However, the molecular mechanism underlying this detrimental condition is currently unclear. Pyruvate dehydrogenase kinase 4 (PDK4), a central regulator of ce...

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Detalles Bibliográficos
Autores principales: Sinam, Ibotombi Singh, Chanda, Dipanjan, Thoudam, Themis, Kim, Min‐Ji, Kim, Byung‐Gyu, Kang, Hyeon‐Ji, Lee, Jung Yi, Baek, Seung‐Hoon, Kim, Shin‐Yoon, Shim, Bum Jin, Ryu, Dongryeol, Jeon, Jae‐Han, Lee, In‐Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745560/
https://www.ncbi.nlm.nih.gov/pubmed/36259412
http://dx.doi.org/10.1002/jcsm.13100