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Combinatorial Methylerythritol Phosphate Pathway Engineering and Process Optimization for Increased Menaquinone-7 Synthesis in Bacillus subtilis

Vitamin K2 (menaquinone) is an essential vitamin existing in the daily diet, and menaquinone-7 (MK- 7) is an important form of it. In a recent work, we engineered the synthesis modules of MK-7 in Bacillus subtilis, and the strain BS20 could produce 360 mg/l MK-7 in shake flasks, while the methyleryt...

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Detalles Bibliográficos
Autores principales:	Chen, Taichi, Xia, Hongzhi, Cui, Shixiu, Lv, Xueqin, Li, Xueliang, Liu, Yanfeng, Li, Jianghua, Du, Guocheng, Liu, Long
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Microbiology and Biotechnology 2020
Materias:	Research article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745656/ https://www.ncbi.nlm.nih.gov/pubmed/32482943 http://dx.doi.org/10.4014/jmb.1912.12008

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