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Cisplatin exposure acutely disrupts mitochondrial bioenergetics in the zebrafish lateral-line organ

Cisplatin is a commonly used chemotherapeutic agent that causes debilitating high-frequency hearing loss. No targeted therapies currently exist to treat cisplatin ototoxicity, partly because the underlying mechanisms of cisplatin-induced hair cell damage are not completely defined. Zebrafish may off...

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Detalles Bibliográficos
Autores principales: Lee, David S., Schrader, Angela, Warchol, Mark, Sheets, Lavinia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745743/
https://www.ncbi.nlm.nih.gov/pubmed/35534350
http://dx.doi.org/10.1016/j.heares.2022.108513

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