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A Rare Case of Cardiac Metastasis from Colon Cancer

It is very rare for colorectal neoplasms to metastasize to the heart in the worldwide medical literature; only a single case of well-documented colorectal cancer metastasis to the left atrium was found. The case of a 66-year-old man is explained in this paper, who was suffering from metastatic adeno...

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Autores principales: Modabber, Zahra, Pourkia, Roghayeh, Vafaey, Hamidreza, Alizadeh, Ali, Ranaee, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Society of Pathology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745759/
https://www.ncbi.nlm.nih.gov/pubmed/36532640
http://dx.doi.org/10.30699/IJP.2022.551822.2874
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author Modabber, Zahra
Pourkia, Roghayeh
Vafaey, Hamidreza
Alizadeh, Ali
Ranaee, Mohammad
author_facet Modabber, Zahra
Pourkia, Roghayeh
Vafaey, Hamidreza
Alizadeh, Ali
Ranaee, Mohammad
author_sort Modabber, Zahra
collection PubMed
description It is very rare for colorectal neoplasms to metastasize to the heart in the worldwide medical literature; only a single case of well-documented colorectal cancer metastasis to the left atrium was found. The case of a 66-year-old man is explained in this paper, who was suffering from metastatic adenocarcinoma of the colon that included the left atrium. In transthoracic and transesophageal echocardiography, a large multilobulated mass was present in the left atrium. An accidental pulmonary mass was also seen in a lung spiral CT scan. The cardiac mass was taken out, and a biopsy was obtained from the pulmonary mass. Adenocarcinoma was seen in histological assessment. Immunohistochemical staining was carried out to examine the expression of cytokeratin 7, cytokeratin 20, and caudal-related homeobox transcription factor 2 (CDX2) to determine the origin of the adenocarcinoma. In addition, the expression of these proteins was linked to the attributes of the patient and tumor. Post-surgical transesophageal echocardiography showed normal left ventricle and right ventricle function with no evidence of left atrium mass. Therefore, we suggest that asymptomatic cancer patients with a history of colorectal cancer and who have developed cardiac symptoms should be immediately examined for potential cardiac metastasis.
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spelling pubmed-97457592022-12-16 A Rare Case of Cardiac Metastasis from Colon Cancer Modabber, Zahra Pourkia, Roghayeh Vafaey, Hamidreza Alizadeh, Ali Ranaee, Mohammad Iran J Pathol Case Report It is very rare for colorectal neoplasms to metastasize to the heart in the worldwide medical literature; only a single case of well-documented colorectal cancer metastasis to the left atrium was found. The case of a 66-year-old man is explained in this paper, who was suffering from metastatic adenocarcinoma of the colon that included the left atrium. In transthoracic and transesophageal echocardiography, a large multilobulated mass was present in the left atrium. An accidental pulmonary mass was also seen in a lung spiral CT scan. The cardiac mass was taken out, and a biopsy was obtained from the pulmonary mass. Adenocarcinoma was seen in histological assessment. Immunohistochemical staining was carried out to examine the expression of cytokeratin 7, cytokeratin 20, and caudal-related homeobox transcription factor 2 (CDX2) to determine the origin of the adenocarcinoma. In addition, the expression of these proteins was linked to the attributes of the patient and tumor. Post-surgical transesophageal echocardiography showed normal left ventricle and right ventricle function with no evidence of left atrium mass. Therefore, we suggest that asymptomatic cancer patients with a history of colorectal cancer and who have developed cardiac symptoms should be immediately examined for potential cardiac metastasis. Iranian Society of Pathology 2022 2022-08-02 /pmc/articles/PMC9745759/ /pubmed/36532640 http://dx.doi.org/10.30699/IJP.2022.551822.2874 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution- 4.0 International License (https://creativecommons.org/licenses/by/4.0/) which permits Share, copy and redistribution of the material in any medium or format or adapt, remix, transform, and build upon the material for any purpose, even commercially.
spellingShingle Case Report
Modabber, Zahra
Pourkia, Roghayeh
Vafaey, Hamidreza
Alizadeh, Ali
Ranaee, Mohammad
A Rare Case of Cardiac Metastasis from Colon Cancer
title A Rare Case of Cardiac Metastasis from Colon Cancer
title_full A Rare Case of Cardiac Metastasis from Colon Cancer
title_fullStr A Rare Case of Cardiac Metastasis from Colon Cancer
title_full_unstemmed A Rare Case of Cardiac Metastasis from Colon Cancer
title_short A Rare Case of Cardiac Metastasis from Colon Cancer
title_sort rare case of cardiac metastasis from colon cancer
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745759/
https://www.ncbi.nlm.nih.gov/pubmed/36532640
http://dx.doi.org/10.30699/IJP.2022.551822.2874
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