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RNA modifications: an overview of select web-based tools
The field of epitranscriptomics has expanded dramatically in recent years, both in the number of identified RNA modifications and the number of researchers studying them. As knowledge of post-transcriptional modifications continues to expand, numerous new methods have been developed to detect these...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745833/ https://www.ncbi.nlm.nih.gov/pubmed/36104107 http://dx.doi.org/10.1261/rna.079443.122 |
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author | Ramos, Jillian |
author_facet | Ramos, Jillian |
author_sort | Ramos, Jillian |
collection | PubMed |
description | The field of epitranscriptomics has expanded dramatically in recent years, both in the number of identified RNA modifications and the number of researchers studying them. As knowledge of post-transcriptional modifications continues to expand, numerous new methods have been developed to detect these modifications. Additionally, modifications are being extended to therapeutic settings, such as with recent mRNA vaccines. With this increase in knowledge and use, the community is recognizing the necessity for user-friendly databases to (i) store information from both high- and low-throughput studies and (ii) provide prediction software on how RNA modifications contribute to RNA function and disease. This mini-review highlights select RNA modification databases and their key attributes with the aim of providing a resource to researchers in the field of epitranscriptomics. |
format | Online Article Text |
id | pubmed-9745833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cold Spring Harbor Laboratory Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-97458332023-01-04 RNA modifications: an overview of select web-based tools Ramos, Jillian RNA Mini-Review The field of epitranscriptomics has expanded dramatically in recent years, both in the number of identified RNA modifications and the number of researchers studying them. As knowledge of post-transcriptional modifications continues to expand, numerous new methods have been developed to detect these modifications. Additionally, modifications are being extended to therapeutic settings, such as with recent mRNA vaccines. With this increase in knowledge and use, the community is recognizing the necessity for user-friendly databases to (i) store information from both high- and low-throughput studies and (ii) provide prediction software on how RNA modifications contribute to RNA function and disease. This mini-review highlights select RNA modification databases and their key attributes with the aim of providing a resource to researchers in the field of epitranscriptomics. Cold Spring Harbor Laboratory Press 2022-11 /pmc/articles/PMC9745833/ /pubmed/36104107 http://dx.doi.org/10.1261/rna.079443.122 Text en © 2022 Ramos; Published by Cold Spring Harbor Laboratory Press for the RNA Society https://creativecommons.org/licenses/by-nc/4.0/This article, published in RNA, is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Mini-Review Ramos, Jillian RNA modifications: an overview of select web-based tools |
title | RNA modifications: an overview of select web-based tools |
title_full | RNA modifications: an overview of select web-based tools |
title_fullStr | RNA modifications: an overview of select web-based tools |
title_full_unstemmed | RNA modifications: an overview of select web-based tools |
title_short | RNA modifications: an overview of select web-based tools |
title_sort | rna modifications: an overview of select web-based tools |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745833/ https://www.ncbi.nlm.nih.gov/pubmed/36104107 http://dx.doi.org/10.1261/rna.079443.122 |
work_keys_str_mv | AT ramosjillian rnamodificationsanoverviewofselectwebbasedtools |