Cargando…
Knockouts of TUT7 and 3′hExo show that they cooperate in histone mRNA maintenance and degradation
Metazoan histone mRNAs are the only cellular eukaryotic mRNAs that are not polyadenylated, ending instead in a conserved stem–loop. SLBP is bound to the 3′ end of histone mRNAs and is required for translation of histone mRNA. The expression of histone mRNAs is tightly cell-cycle regulated. A major r...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745837/ https://www.ncbi.nlm.nih.gov/pubmed/36041871 http://dx.doi.org/10.1261/rna.079233.122 |