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Diagnosis and management of Parkinson’s disease dementia and dementia with Lewy bodies: recommendations of the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology

Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) represent the second most common type of degenerative dementia in patients aged 65 years and older, leading to progressive cognitive dysfunction and impaired quality of life. This study aims to provide a consensus based on a syst...

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Detalles Bibliográficos
Autores principales: Parmera, Jacy Bezerra, Tumas, Vitor, Ferraz, Henrique Ballalai, Spitz, Mariana, Barbosa, Maira Tonidandel, Smid, Jerusa, Barbosa, Breno José Alencar Pires, Schilling, Lucas Porcello, Balthazar, Márcio Luiz Figueiredo, de Souza, Leonardo Cruz, Vale, Francisco Assis Carvalho, Caramelli, Paulo, Bertolucci, Paulo Henrique Ferreira, Chaves, Márcia Lorena Fagundes, Brucki, Sonia Maria Dozzi, Nitrini, Ricardo, Castilhos, Raphael Machado, Frota, Norberto Anízio Ferreira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academia Brasileira de Neurologia, Departamento de Neurologia Cognitiva e Envelhecimento 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745997/
https://www.ncbi.nlm.nih.gov/pubmed/36533156
http://dx.doi.org/10.1590/1980-5764-DN-2022-S105PT
Descripción
Sumario:Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB) represent the second most common type of degenerative dementia in patients aged 65 years and older, leading to progressive cognitive dysfunction and impaired quality of life. This study aims to provide a consensus based on a systematic Brazilian literature review and a comprehensive international review concerning PDD and DLB. Moreover, we sought to report on and give recommendations about the best diagnostic approaches focusing on primary and secondary care. Based on the available data, we recommend clinicians to apply at least one brief global cognitive instrument to assess PDD, such as the Mini-Mental State Examination and preferably the Montreal Cognitive Assessment and the Addenbrooke’s Cognitive Examination-Revised. Validated instruments to accurately assess functional abilities in Brazilian PD patients are still incipient. Further studies should focus on biomarkers with Brazilian cohorts.