Cargando…

Gankyrin and TIGAR cooperatively accelerate glucose metabolism toward the PPP and TCA cycle in hepatocellular carcinoma

Oncogene‐derived metabolic reprogramming is important for anabolic growth of cancer cells, which is now considered to be not simply rely on glycolysis. Pentose phosphate pathway and tricarboxylic acid cycle also play pivotal roles in helping cancer cells to meet their anabolic and energy demands. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Chun, Cui, Xiao‐wen, Ding, Zhi‐wen, Jiang, Tian‐yi, Feng, Xiao‐fan, Pan, Yu‐fei, Lin, Yun‐kai, Shang, Tai‐yu, Wang, Qing, Pan, Jian, Wang, Jian, Wang, Hong‐yang, Dong, Li‐wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746032/ https://www.ncbi.nlm.nih.gov/pubmed/36114745 http://dx.doi.org/10.1111/cas.15593

Ejemplares similares

Dexamethasone enhances glucose uptake by SGLT1 and GLUT1 and boosts ATP generation through the PPP-TCA cycle in bovine neutrophils
por: Wang, Xinbo, et al.
Publicado: (2022)

Gankyrin has an antioxidative role through the feedback regulation of Nrf2 in hepatocellular carcinoma
por: Yang, Chun, et al.
Publicado: (2016)

TIGAR, TIGAR, burning bright
por: Lee, Pearl, et al.
Publicado: (2014)

Gankyrin gene deletion followed by proteomic analysis: insight into the roles of Gankyrin in Tumorigenesis and Metastasis
por: Luo, Xue, et al.
Publicado: (2012)

The Regulation of TIGAR
por: Lee, Pearl, et al.
Publicado: (2014)

Discovery of a small-molecule binder of the oncoprotein gankyrin that modulates gankyrin activity in the cell
por: Chattopadhyay, Anasuya, et al.
Publicado: (2016)

The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry
por: Liu, Xujun, et al.
Publicado: (2021)

Gankyrin activates the hedgehog signalling to drive metastasis in osteosarcoma
por: Wang, Chongchong, et al.
Publicado: (2021)

Phosphorylation of PDHA by AMPK Drives TCA Cycle to Promote Cancer Metastasis
por: Cai, Zhen, et al.
Publicado: (2020)

Changes in TCA cycle and TCA cycle-related metabolites in plasma upon citric acid administration in rats
por: Hara, Yurie, et al.
Publicado: (2021)

Gankyrin is a novel biomarker for disease progression and prognosis of patients with renal cell carcinoma
por: Wang, Chao, et al.
Publicado: (2018)

Exposure of ELF-EMF and RF-EMF Increase the Rate of Glucose Transport and TCA Cycle in Budding Yeast
por: Lin, Kang-Wei, et al.
Publicado: (2016)

Activation of the TCA Cycle to Provide Immune Protection in Zebrafish Immunized by High Magnesium-Prepared Vibrio alginolyticus Vaccine
por: Yang, Jun, et al.
Publicado: (2021)

Rescue of TCA Cycle Dysfunction for Cancer Therapy
por: Marquez, Jubert, et al.
Publicado: (2019)

Identification and characterization of the TCA cycle genes in maize
por: Liu, Yongming, et al.
Publicado: (2019)

TIGAR Attenuates High Glucose-Induced Neuronal Apoptosis via an Autophagy Pathway
por: Zhou, Wenjuan, et al.
Publicado: (2019)

TIGAR/AP-1 axis accelerates the division of Lgr5(−) reserve intestinal stem cells to reestablish intestinal architecture after lethal radiation
por: Chen, Fei, et al.
Publicado: (2020)

Analysis of BDS Fractional Cycle Biases and PPP Ambiguity Resolution
por: Jiang, Weiping, et al.
Publicado: (2019)

TCA cycle enhancement and uptake of monomeric substrates support growth of marine Roseobacter at low temperature
por: Wang, Meng, et al.
Publicado: (2022)

Alanine-specific appetite in slow growing chickens is associated with impaired glucose transport and TCA cycle
por: Niknafs, Shahram, et al.
Publicado: (2022)

Gankyrin as Potential Biomarker for Colorectal Cancer With Occult Liver Metastases
por: Wang, Chengxing, et al.
Publicado: (2021)

TIGAR cooperated with glycolysis to inhibit the apoptosis of leukemia cells and associated with poor prognosis in patients with cytogenetically normal acute myeloid leukemia
por: Qian, Sixuan, et al.
Publicado: (2016)

Gradually elevated expression of Gankyrin during human hepatocarcinogenesis and its clinicopathological significance
por: Jing, Hongbiao, et al.
Publicado: (2014)

The role of TIGAR in nervous system diseases
por: Huang, Bei, et al.
Publicado: (2022)

TIGAR Protects Cochlear Hair Cells against Teicoplanin-Induced Damage
por: Zhang, Qiongmin, et al.
Publicado: (2023)

Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia
por: Feng, Tzu-Yu, et al.
Publicado: (2023)

High Glucose Activates Prolyl Hydroxylases and Disrupts HIF-α Signaling via the P53/TIGAR Pathway in Cardiomyocyte
por: Chen, Jian-Xiong, et al.
Publicado: (2023)

Sirtuin 3 Alleviates Diabetic Cardiomyopathy by Regulating TIGAR and Cardiomyocyte Metabolism
por: Li, Lanfang, et al.
Publicado: (2021)

The in vivo function of TIGAR, a p53 target gene that regulates glucose metabolism
por: Cheung, Eric, et al.
Publicado: (2014)

Mitochondrial metabolism in TCA cycle mutant cancer cells
por: Sullivan, Lucas B, et al.
Publicado: (2014)

The emerging role and targetability of the TCA cycle in cancer metabolism
por: Anderson, Nicole M., et al.
Publicado: (2017)

Mitochondrial TCA cycle metabolites control physiology and disease
por: Martínez-Reyes, Inmaculada, et al.
Publicado: (2020)

Operation of a TCA cycle subnetwork in the mammalian nucleus
por: Kafkia, Eleni, et al.
Publicado: (2022)

Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo
por: Zhao, Yiqing, et al.
Publicado: (2019)

Effective Cycle Slip Detection and Repair for PPP/INS Integrated Systems
por: Yang, Sheng, et al.
Publicado: (2019)

Nuclear localization of mitochondrial TCA cycle enzymes modulates pluripotency via histone acetylation
por: Li, Wei, et al.
Publicado: (2022)

TIGAR knockdown radiosensitizes TrxR1-overexpressing glioma in vitro and in vivo via inhibiting Trx1 nuclear transport
por: Zhang, Yushuo, et al.
Publicado: (2017)

Gankyrin Is Frequently Overexpressed in Cervical High Grade Disease and Is Associated with Cervical Carcinogenesis and Metastasis
por: Liu, Yuan, et al.
Publicado: (2014)

Boosted TCA cycle enhances survival of zebrafish to Vibrio alginolyticus infection
por: Yang, Man-Jun, et al.
Publicado: (2018)

Gankyrin is a predictive and oncogenic factor in well-differentiated and dedifferentiated liposarcoma
por: Hwang, Ju-Ae, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_qus0eebjc8e0msv3jeddv0mvkt