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Alvocidib inhibits IRF4 expression via super‐enhancer suppression and adult T‐cell leukemia/lymphoma cell growth
Adult T‐cell leukemia/lymphoma (ATL) is an intractable hematological malignancy with extremely poor prognosis. Recent studies have revealed that super‐enhancers (SE) play important roles in controlling tumor‐specific gene expression and are potential therapeutic targets for neoplastic diseases inclu...
Autores principales: | Sakamoto, Hikaru, Ando, Koji, Imaizumi, Yoshitaka, Mishima, Hiroyuki, Kinoshita, Akira, Kobayashi, Yuji, Kitanosono, Hideaki, Kato, Takeharu, Sawayama, Yasushi, Sato, Shinya, Hata, Tomoko, Nakashima, Masahiro, Yoshiura, Koh‐Ichiro, Miyazaki, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746047/ https://www.ncbi.nlm.nih.gov/pubmed/36047964 http://dx.doi.org/10.1111/cas.15550 |
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