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CGRP-dependent sensitization of PKC-δ positive neurons in central amygdala mediates chronic migraine

BACKGROUND: To investigate specific brain regions and neural circuits that are responsible for migraine chronification. METHODS: We established a mouse model of chronic migraine with intermittent injections of clinically-relevant dose of nitroglycerin (0.1 mg/kg for 9 days) and validated the model w...

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Detalles Bibliográficos
Autores principales:	Chou, Tse-Ming, Lee, Zhung-Fu, Wang, Shuu-Jiun, Lien, Cheng-Chang, Chen, Shih-Pin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Milan 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746101/ https://www.ncbi.nlm.nih.gov/pubmed/36510143 http://dx.doi.org/10.1186/s10194-022-01531-8

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