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hUCMSCs carrying exenatide prevent T1DM by improving intestinal microflora composition and islet tissue damage repair
BACKGROUND: Exenatide is a stable analogue of glucagon-like peptide 1 that can reduce postprandial hyperglycemia and has been utilized as adjunctive therapy for type 1 diabetes mellitus (T1DM). The human umbilical cord is a rich source of MSCs, and human umbilical cord mesenchymal stem cells (hUCMSC...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746121/ https://www.ncbi.nlm.nih.gov/pubmed/36514009 http://dx.doi.org/10.1186/s10020-022-00526-0 |