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Inflammatory ocular events after inactivated COVID-19 vaccination

To report potential vaccine-induced inflammatory ocular adverse events following inactivated COVID-19 vaccination. Retrospective study of patients with uveitis and other ocular complications following inactivated coronavirus disease 2019 (COVID-19) vaccination at a tertiary referral center between M...

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Autores principales: Fei, Ping, Feng, Huazhang, Li, Jing, Liu, Miaomiao, Luo, Jia, Ye, Hongfei, Zhao, Peiquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746467/
https://www.ncbi.nlm.nih.gov/pubmed/36369840
http://dx.doi.org/10.1080/21645515.2022.2138051
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author Fei, Ping
Feng, Huazhang
Li, Jing
Liu, Miaomiao
Luo, Jia
Ye, Hongfei
Zhao, Peiquan
author_facet Fei, Ping
Feng, Huazhang
Li, Jing
Liu, Miaomiao
Luo, Jia
Ye, Hongfei
Zhao, Peiquan
author_sort Fei, Ping
collection PubMed
description To report potential vaccine-induced inflammatory ocular adverse events following inactivated COVID-19 vaccination. Retrospective study of patients with uveitis and other ocular complications following inactivated coronavirus disease 2019 (COVID-19) vaccination at a tertiary referral center between May 2021 and August 2021. Data collection consisted of demographic and clinical data. The study included 8 eyes of 5 patients (4 females, 1 male), with a mean age of 37.2 ± 12.5 years (range 28–59 years). Mean time between vaccination and ocular complications onset was 13.2 ± 11.9 days (range 3–30 days), including two patients after the first dose of the vaccine and 3 patients after the second dose. The cases reported were three anterior uveitis, one herpetic keratitis and iridocyclitis, and one posterior uveitis. Patients received treatment with local and/or systemic steroids and all the patients had good visual outcomes. Ocular inflammatory events may occur after vaccination with possible gender preponderance. However, they are rare and manageable. Overall, the efficacy and safety of vaccination should be emphasized.
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spelling pubmed-97464672022-12-14 Inflammatory ocular events after inactivated COVID-19 vaccination Fei, Ping Feng, Huazhang Li, Jing Liu, Miaomiao Luo, Jia Ye, Hongfei Zhao, Peiquan Hum Vaccin Immunother Coronavirus – Research Article To report potential vaccine-induced inflammatory ocular adverse events following inactivated COVID-19 vaccination. Retrospective study of patients with uveitis and other ocular complications following inactivated coronavirus disease 2019 (COVID-19) vaccination at a tertiary referral center between May 2021 and August 2021. Data collection consisted of demographic and clinical data. The study included 8 eyes of 5 patients (4 females, 1 male), with a mean age of 37.2 ± 12.5 years (range 28–59 years). Mean time between vaccination and ocular complications onset was 13.2 ± 11.9 days (range 3–30 days), including two patients after the first dose of the vaccine and 3 patients after the second dose. The cases reported were three anterior uveitis, one herpetic keratitis and iridocyclitis, and one posterior uveitis. Patients received treatment with local and/or systemic steroids and all the patients had good visual outcomes. Ocular inflammatory events may occur after vaccination with possible gender preponderance. However, they are rare and manageable. Overall, the efficacy and safety of vaccination should be emphasized. Taylor & Francis 2022-11-11 /pmc/articles/PMC9746467/ /pubmed/36369840 http://dx.doi.org/10.1080/21645515.2022.2138051 Text en © 2022 The Author(s). Published with license by Taylor & Francis Group, LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
spellingShingle Coronavirus – Research Article
Fei, Ping
Feng, Huazhang
Li, Jing
Liu, Miaomiao
Luo, Jia
Ye, Hongfei
Zhao, Peiquan
Inflammatory ocular events after inactivated COVID-19 vaccination
title Inflammatory ocular events after inactivated COVID-19 vaccination
title_full Inflammatory ocular events after inactivated COVID-19 vaccination
title_fullStr Inflammatory ocular events after inactivated COVID-19 vaccination
title_full_unstemmed Inflammatory ocular events after inactivated COVID-19 vaccination
title_short Inflammatory ocular events after inactivated COVID-19 vaccination
title_sort inflammatory ocular events after inactivated covid-19 vaccination
topic Coronavirus – Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746467/
https://www.ncbi.nlm.nih.gov/pubmed/36369840
http://dx.doi.org/10.1080/21645515.2022.2138051
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