Bystander CD4(+) T cells infiltrate human tumors and are phenotypically distinct

Tumor-specific T cells likely underpin effective immune checkpoint-blockade therapies. Yet, most studies focus on Treg cells and CD8(+) tumor-infiltrating lymphocytes (TILs). Here, we study CD4(+) TILs in human lung and colorectal cancers and observe that non-Treg CD4(+) TILs average more than 70% o...

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Detalles Bibliográficos
Autores principales: Li, Shamin, Zhuang, Summer, Heit, Antja, Koo, Si-Lin, Tan, Aaron C., Chow, I-Ting, Kwok, William W., Tan, Iain Beehuat, Tan, Daniel S.W., Simoni, Yannick, Newell, Evan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746624/
https://www.ncbi.nlm.nih.gov/pubmed/36524209
http://dx.doi.org/10.1080/2162402X.2021.2012961

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