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Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac

BACKGROUND: Monte Carlo simulation is generally appreciated as an extraordinary technique to investigate particle physics processes and interactions in nuclear medicine and Radiation Therapy. The present task validates a new methodology of Monte Carlo simulation based on the Multithreading technique...

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Autores principales: Krim, Deae-eddine, Rrhioua, Abdeslem, Zerfaoui, Mustapha, Bakari, Dikra, Hamal, Mohammed, Moukhlissi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Via Medica 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746635/
https://www.ncbi.nlm.nih.gov/pubmed/36523798
http://dx.doi.org/10.5603/RPOR.a2022.0096
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author Krim, Deae-eddine
Rrhioua, Abdeslem
Zerfaoui, Mustapha
Bakari, Dikra
Hamal, Mohammed
Moukhlissi, Mohamed
author_facet Krim, Deae-eddine
Rrhioua, Abdeslem
Zerfaoui, Mustapha
Bakari, Dikra
Hamal, Mohammed
Moukhlissi, Mohamed
author_sort Krim, Deae-eddine
collection PubMed
description BACKGROUND: Monte Carlo simulation is generally appreciated as an extraordinary technique to investigate particle physics processes and interactions in nuclear medicine and Radiation Therapy. The present task validates a new methodology of Monte Carlo simulation based on the Multithreading technique to reduce CPU time to simulate a 6 MV photon beam provided by the Elekta Synergy MLCi2 platform medical linear accelerator treatment head utilizing TOpas version 3.6 Monte Carlo software and the Slurm Marwan cluster. MATERIALS AND METHODS: The simulation includes the linear accelerator (LINAC) major components. Calculations are performed for the photon beam with several treatment field sizes varying from 3 × 3 to 10 × 10 cm(2) at a 100 cm of distance from the source to the surface of the IBA dosimetry water box. The simulation was wholly approved by comparison with experimental distributions. To evaluate simulation accuracy, gamma index formalism for (2%/2mm) and (3%/2mm) criteria, Distance To Agreement DTA, and the estimator standard error ɛ and ɛ(max) are used. RESULTS: Good agreement between simulations and measurements was observed for depth doses and lateral dose profiles, respectively. The gamma index comparisons also highlighted this agreement; more than 97% of the points for all simulations satisfy the quality assurance criteria of (2%/2mm). Regarding calculation performance, the event processing speed is faster using Gate-[mp] compared to TOpas-[mt] mode when running the identical simulation code for both. CONCLUSIONS: Consequently, according to the achieved results, the proposed methodology shows the first validation of TOpas in radiotherapy linacs simulations and a reduction in calculation time, capping simulation accuracy as much as possible. For this reason, this software is recommended to be serviceable for Treatment Planning Systems (TPS) purposes.
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spelling pubmed-97466352022-12-14 Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac Krim, Deae-eddine Rrhioua, Abdeslem Zerfaoui, Mustapha Bakari, Dikra Hamal, Mohammed Moukhlissi, Mohamed Rep Pract Oncol Radiother Research Paper BACKGROUND: Monte Carlo simulation is generally appreciated as an extraordinary technique to investigate particle physics processes and interactions in nuclear medicine and Radiation Therapy. The present task validates a new methodology of Monte Carlo simulation based on the Multithreading technique to reduce CPU time to simulate a 6 MV photon beam provided by the Elekta Synergy MLCi2 platform medical linear accelerator treatment head utilizing TOpas version 3.6 Monte Carlo software and the Slurm Marwan cluster. MATERIALS AND METHODS: The simulation includes the linear accelerator (LINAC) major components. Calculations are performed for the photon beam with several treatment field sizes varying from 3 × 3 to 10 × 10 cm(2) at a 100 cm of distance from the source to the surface of the IBA dosimetry water box. The simulation was wholly approved by comparison with experimental distributions. To evaluate simulation accuracy, gamma index formalism for (2%/2mm) and (3%/2mm) criteria, Distance To Agreement DTA, and the estimator standard error ɛ and ɛ(max) are used. RESULTS: Good agreement between simulations and measurements was observed for depth doses and lateral dose profiles, respectively. The gamma index comparisons also highlighted this agreement; more than 97% of the points for all simulations satisfy the quality assurance criteria of (2%/2mm). Regarding calculation performance, the event processing speed is faster using Gate-[mp] compared to TOpas-[mt] mode when running the identical simulation code for both. CONCLUSIONS: Consequently, according to the achieved results, the proposed methodology shows the first validation of TOpas in radiotherapy linacs simulations and a reduction in calculation time, capping simulation accuracy as much as possible. For this reason, this software is recommended to be serviceable for Treatment Planning Systems (TPS) purposes. Via Medica 2022-10-31 /pmc/articles/PMC9746635/ /pubmed/36523798 http://dx.doi.org/10.5603/RPOR.a2022.0096 Text en © 2022 Greater Poland Cancer Centre https://creativecommons.org/licenses/by-nc-nd/4.0/This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially
spellingShingle Research Paper
Krim, Deae-eddine
Rrhioua, Abdeslem
Zerfaoui, Mustapha
Bakari, Dikra
Hamal, Mohammed
Moukhlissi, Mohamed
Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac
title Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac
title_full Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac
title_fullStr Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac
title_full_unstemmed Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac
title_short Validation of Monte Carlo multithreading TOpas 3.6 software in order to simulate the 6 MV Elekta Synergy MLCi2 platform linac
title_sort validation of monte carlo multithreading topas 3.6 software in order to simulate the 6 mv elekta synergy mlci2 platform linac
topic Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746635/
https://www.ncbi.nlm.nih.gov/pubmed/36523798
http://dx.doi.org/10.5603/RPOR.a2022.0096
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