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Venetoclax Plus Gilteritinib for FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia
The FMS-related tyrosine kinase 3 (FLT3) inhibitor gilteritinib is standard therapy for relapsed/refractory FLT3-mutated (FLT3(mut)) acute myeloid leukemia (AML) but seldom reduces FLT3(mut) burden or induces sustained efficacy. Gilteritinib combines synergistically with the BCL-2 inhibitor venetocl...
Autores principales: | Daver, Naval, Perl, Alexander E., Maly, Joseph, Levis, Mark, Ritchie, Ellen, Litzow, Mark, McCloskey, James, Smith, Catherine C., Schiller, Gary, Bradley, Terrence, Tiu, Ramon V., Naqvi, Kiran, Dail, Monique, Brackman, Deanna, Siddani, Satya, Wang, Jing, Chyla, Brenda, Lee, Paul, Altman, Jessica K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746764/ https://www.ncbi.nlm.nih.gov/pubmed/35849791 http://dx.doi.org/10.1200/JCO.22.00602 |
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