NLRC4-mediated activation of CD1c(+) DC contributes to perpetuation of synovitis in rheumatoid arthritis

The individual contribution of specific myeloid subsets such as CD1c(+) conventional DC (cDC) to perpetuation of rheumatoid arthritis (RA) pathology remains unclear. In addition, the specific innate sensors driving pathogenic activation of CD1c(+) cDC in patients with RA and their functional implica...

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Detalles Bibliográficos
Autores principales: Delgado-Arévalo, Cristina, Calvet-Mirabent, Marta, Triguero-Martínez, Ana, Vázquez de Luis, Enrique, Benguría-Filippini, Alberto, Largo, Raquel, Calzada-Fraile, Diego, Popova, Olga, Sánchez-Cerrillo, Ildefonso, Tsukalov, Ilya, Moreno-Vellisca, Roberto, de la Fuente, Hortensia, Herrero-Beaumont, Gabriel, Ramiro, Almudena, Sánchez-Madrid, Francisco, Castañeda, Santos, Dopazo, Ana, González Álvaro, Isidoro, Martin-Gayo, Enrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746818/
https://www.ncbi.nlm.nih.gov/pubmed/36194479
http://dx.doi.org/10.1172/jci.insight.152886

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