Pathogenicity and impact of HLA class I alleles in aplastic anemia patients of different ethnicities

Acquired aplastic anemia (AA) is caused by autoreactive T cell–mediated destruction of early hematopoietic cells. Somatic loss of human leukocyte antigen (HLA) class I alleles was identified as a mechanism of immune escape in surviving hematopoietic cells of some patients with AA. However, pathogeni...

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Detalles Bibliográficos
Autores principales: Olson, Timothy S., Frost, Benjamin F., Duke, Jamie L., Dribus, Marian, Xie, Hongbo M., Prudowsky, Zachary D., Furutani, Elissa, Gudera, Jonas, Shah, Yash B., Ferriola, Deborah, Dinou, Amalia, Pagkrati, Ioanna, Kim, Soyoung, Xu, Yixi, He, Meilun, Zheng, Shannon, Nijim, Sally, Lin, Ping, Xu, Chong, Nakano, Taizo A., Oved, Joseph H., Carreno, Beatriz M., Bolon, Yung-Tsi, Gadalla, Shahinaz M., Marsh, Steven G.E., Paczesny, Sophie, Lee, Stephanie J., Monos, Dimitrios S., Shimamura, Akiko, Bertuch, Alison A., Gragert, Loren, Spellman, Stephen R., Babushok, Daria V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746824/
https://www.ncbi.nlm.nih.gov/pubmed/36219480
http://dx.doi.org/10.1172/jci.insight.163040

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