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Airway surface hyperviscosity and defective mucociliary transport by IL-17/TNF-α are corrected by β-adrenergic stimulus
The fluid covering the surface of airway epithelia represents a first barrier against pathogens. The chemical and physical properties of the airway surface fluid are controlled by the activity of ion channels and transporters. In cystic fibrosis (CF), loss of CFTR chloride channel function causes ai...
Autores principales: | Guidone, Daniela, Buccirossi, Martina, Scudieri, Paolo, Genovese, Michele, Sarnataro, Sergio, De Cegli, Rossella, Cresta, Federico, Terlizzi, Vito, Planelles, Gabrielle, Crambert, Gilles, Sermet, Isabelle, Galietta, Luis J.V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746827/ https://www.ncbi.nlm.nih.gov/pubmed/36219481 http://dx.doi.org/10.1172/jci.insight.164944 |
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