An ELF4 hypomorphic variant results in NK cell deficiency

NK cell deficiencies (NKD) are a type of primary immune deficiency in which the major immunologic abnormality affects NK cell number, maturity, or function. Since NK cells contribute to immune defense against virally infected cells, patients with NKD experience higher susceptibility to chronic, recu...

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Detalles Bibliográficos
Autores principales: Salinas, Sandra Andrea, Mace, Emily M., Conte, Matilde I., Park, Chun Shik, Li, Yu, Rosario-Sepulveda, Joshua I., Mahapatra, Sanjana, Moore, Emily K., Hernandez, Evelyn R., Chinn, Ivan K., Reed, Abigail E., Lee, Barclay J., Frumovitz, Alexander, Gibbs, Richard A., Posey, Jennifer E., Forbes Satter, Lisa R., Thatayatikom, Akaluck, Allenspach, Eric J., Wensel, Theodore G., Lupski, James R., Lacorazza, H. Daniel, Orange, Jordan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746917/
https://www.ncbi.nlm.nih.gov/pubmed/36477361
http://dx.doi.org/10.1172/jci.insight.155481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746917/
https://www.ncbi.nlm.nih.gov/pubmed/36477361
http://dx.doi.org/10.1172/jci.insight.155481

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