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Analysis of the evolution of resistance to multiple antibiotics enables prediction of the Escherichia coli phenotype-based fitness landscape

The fitness landscape represents the complex relationship between genotype or phenotype and fitness under a given environment, the structure of which allows the explanation and prediction of evolutionary trajectories. Although previous studies have constructed fitness landscapes by comprehensively s...

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Detalles Bibliográficos
Autores principales: Iwasawa, Junichiro, Maeda, Tomoya, Shibai, Atsushi, Kotani, Hazuki, Kawada, Masako, Furusawa, Chikara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9746992/
https://www.ncbi.nlm.nih.gov/pubmed/36512529
http://dx.doi.org/10.1371/journal.pbio.3001920