Commentary: Constipation caused by anti-calcitonin gene-related peptide migraine therapeutics explained by antagonism of calcitonin gene-related peptide’s motor-stimulating and prosecretory function in the intestine

Calcitonin gene-related peptide (CGRP) pathway-targeted treatments have been shown to be efficacious in the prevention of episodic and chronic migraine. Currently approved therapies include monoclonal antibodies (mAbs) that target CGRP (eptinezumab, fremanezumab, and galcanezumab) and the CGRP recep...

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Detalles Bibliográficos
Autores principales: Mackenzie, Kimberly D., Ortega, Mario, Kessler, Yoel, Campos, Verena Ramirez, Krasenbaum, Lynda J., Carr, Karen, Ning, Xiaoping, Stratton, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9747098/
https://www.ncbi.nlm.nih.gov/pubmed/36523559
http://dx.doi.org/10.3389/fphys.2022.1067274

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